About
A single mission, pursued together
The PCCTC's distinguished investigators work together with industry sponsors to design, implement, and complete hypothesis-driven clinical studies that translate scientific discoveries into improved standards of care.
Our mission
To accelerate the development of cancer therapies and biomarkers through multicenter collaboration. The PCCTC brings investigators, research sites, and industry partners together in a culture of transparent project co-development, and pairs that scientific community with industry-grade CRO services so that well-designed studies are completed efficiently and their results reach patients.
Our history
The PCCTC was initiated in 2005 by the Prostate Cancer Foundation (PCF) and the U.S. Department of Defense (DOD) Prostate Cancer Research Program (PCRP) in response to critically unmet needs identified by physician investigators and patient advocates. To fulfill our mission, we developed a unique infrastructure that has fostered a culture of transparent project co-development between investigators, research sites, and industry partners.
Established as an independent entity in 2014, the PCCTC, LLC is the nation's premier multicenter contract research organization and academic clinical consortium for prostate cancer research. That foundation now supports a portfolio reaching beyond prostate cancer into a diverse array of oncology indications.
By the numbers
>22%of active early-phase prostate cancer clinical trials in the US are PCCTC investigator-led
39therapeutic candidates advanced to phase 3 study, 13 fully FDA-approved
345PCCTC studies activated, enrolling over 18,000 participants
547abstracts and 210 academic papers published from PCCTC research
Our leadership
Management team
Jake VinsonChief Executive Officer
Michael J. Morris, MDScientific Oversight Committee Chair
Charles J. Ryan, MDMedical Director
Sarah WiseSenior Director of Research Operations
Rebecca GreenDirector of Business Development and Strategy
Michelle KarlinDirector of Business Operations and Quality
Tia Higano, MDLead Medical Monitor
Amanda McMannis, PhDDirector of Clinical Operations (Late Phase Research)
Kristina DushajDirector of Clinical Operations (Early Phase Research)
Joy Allen, PhDDirector of Clinical Data Management and Informatics
Shannon Pileggi, PhDDirector of Data Science
Travis Gerke, ScDHead of Applied IntelligenceScientific Oversight Committee
- Michael Morris, MDChairMemorial Sloan Kettering Cancer Center
- Glenn Liu, MDUniversity of Wisconsin – Madison
- Emmanuel Antonarakis, MDUniversity of Minnesota Twin Cities
- Andrew Armstrong, MD, MScDuke University
- Mary-Ellen Taplin, MDDana-Farber Cancer Institute
- Scott Tagawa, MD, MSWeill Medical College of Cornell University
- Heather Cheng, MD, PhDUniversity of Washington
- Rahul Aggarwal, MDUniversity of California, San Francisco
Participating clinical research sites
A network spanning six continents
More than 200 clinical research sites collaborate on PCCTC studies, including academic medical centers, community hospitals, and research institutions. A current list is available upon request.
United States (106)
- Arizona Urology Specialists
- Atrium Health
- Baptist Clinical Research Institute
- Baylor College of Medicine
- Boca Raton Hospital
- California Research Institute
- Carolina Urologic Research Center
- Chesapeake Urology Research Associates
- Christiana Care Health Services, Inc
- City of Hope
- Cleveland Clinic Foundation
- Columbia University
- Comprehensive Cancer Centers of Nevada
- Dana-Farber Cancer Institute
- Dayton Physician's Network
- Delnor Cancer Center
- Doylestown Health
- Duke Cancer Institute
- Durham VA Medical Center
- Easton Hospital
- Florida Urology Partners
- Fox Chase Cancer Center - Temple Health
- Hematology & Oncology Associates of the Treasure Coast
- Houston Methodist Research Institute
- Howard University
- Indiana University
- Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center
- Karmanos Cancer Institute
- Kishwaukee Cancer Center
- Lahey Clinic
- Lifespan Health - Brown University
- MD Anderson / Banner Health
- MD Anderson / Cooper Health
- Mayo Clinic – Arizona
- Mayo Clinic – Jacksonville
- Mayo Clinic – Rochester
- Medical University of South Carolina
- Memorial Sloan Kettering Cancer Center
- Memphis VA Medical Center
- Midlantic Urology
- Millennium Oncologists
- Moffitt Cancer Center
- Morehouse School of Medicine
- Mount Sinai Medical Center - Miami
- Nebraska Cancer Specialists
- Nevada Cancer Research Foundation (SNCRF)
- New Jersey Urology / Summit Health
- New Mexico Oncology & Hematology Consultants
- New York University
- NewYork–Presbyterian Brooklyn Methodist Hospital
- NorthShore University Health System
- Northwestern Medicine Warrenville & Delnor
- Ochsner Health
- Ohio State University
- Oncology & Hematology Associates of Southwest Virginia
- Oregon Health & Sciences University Knight Cancer Institute
- Ralph H. Johnson VA Medical Center
- Reading Health System
- Rhode Island Hospital
- Robert H. Lurie Comprehensive Cancer Center Northwestern University
- Rocky Mountain Cancer Centers
- Roswell Park Comprehensive Cancer Center
- Rush University Medical Center
- Rutgers University Cancer Institute of New Jersey
- SUNY Buffalo
- San Bernardino Urological Associates
- Tennessee Cancer Specialists
- The University of Chicago
- Thomas Jefferson University - Sidney Kimmel Cancer Center
- Tulane University
- University Hospitals Cleveland Medical Center
- University of Alabama-Birmingham
- University of Alabama-Tuscaloosa
- University of California, Davis
- University of California, Los Angeles
- University of California, San Diego
- University of California, San Francisco
- University of Cincinnati
- University of Florida
- University of Illinois at Chicago
- University of Maryland
- University of Massachusetts
- University of Massachusetts Memorial Medical Center
- University of Michigan
- University of Minnesota
- University of Mississippi Medical Center
- University of New Mexico
- University of North Carolina
- University of Oklahoma Stephenson Cancer Center
- University of Rochester Medical Center
- University of Texas, Southwestern Medical Center
- University of Utah
- University of Virginia
- University of Washington - Fred Hutch Cancer Center
- University of Wisconsin - Carbone Cancer Center
- Urology San Antonio - USA Clinical Trials
- VA of Western New York Healthcare System
- Virginia Cancer Specialists
- Virginia Oncology Associates
- Warrenville Cancer Center
- Washington University in St. Louis
- Weill Cornell Medical Center
- William Jennings Bryan Dorn VA Medical Center
- Winship Cancer Institute Emory University
- XCancer Network
- Yale University
International (108)
- A Beneficiência Portuguesa de São Paulo (Brazil)
- Alfred Health (Australia)
- Arthur J.E. Child Comprehensive Cancer Center (Canada)
- Australian Prostate Centre (Australia)
- Australian Urology Associates (Australia)
- BC Cancer Agency (Canada)
- Beacon Hospital (Ireland)
- CHU de Québec-Université Laval (Canada)
- Canisius Wilhelmina Ziekenhuis (The Netherlands)
- Centre Hospitalier de l'Université de Montréal (Canada)
- Centro de Paulista de Oncologia (Brazil)
- Centro de Pesquisa São Lucas (PUCRS) (Brazil)
- Centro de Pesquisa em Oncologia (Brazil)
- Chris O'Brien Lifehouse (Australia)
- Clatterbridge Cancer Centre NHS Foundation Trust (UK)
- Consorci Hospitalari Provincial de Castelló (Spain)
- Cross Cancer Institute (Canada)
- Deventer Ziekenhuis (The Netherlands)
- Eastern Health (Australia)
- Ente Ospedaliero Cantonale (EOC) (Switzerland)
- Epworth Healthcare (Australia)
- Erasmus Medical Center (The Netherlands)
- Federal Medical Centre Abeokuta (Nigeria)
- Franciscus Gasthuis (The Netherlands)
- Fundación Instituto Valenciano De Oncología (Spain)
- Groote Schuur Hospital (South Africa)
- Guy’s and St Thomas’ NHS Foundation Trust (UK)
- Hospital 12 de Octubre (Spain)
- Hospital Beneficência Portuguesa (Brazil)
- Hospital Clinico San Carlos (Spain)
- Hospital Clínic de Barcelona (Spain)
- Hospital Das Clínicas Da Universidade Federal De Minas Gerais (HC-UFMG) (Brazil)
- Hospital Erasto Gaertner (Brazil)
- Hospital Israelita Albert Einstein (Brazil)
- Hospital Moinhos de Vento (Brazil)
- Hospital Universitario 12 de Octubre (Spain)
- Hospital Universitario Central de Asturias (Spain)
- Hospital Universitario La Princesa (Spain)
- Hospital Universitario Miguel Servet (Zaragoza) (Spain)
- Hospital Universitario Ramón y Cajal (Spain)
- Hospital Universitario Virgen de la Victoria (Spain)
- Hospital University Virgen del Rocio (Spain)
- Hospital de Amor de Barretos (Brazil)
- Hospital del Mar (Spain)
- Hunting-St. Antonius (Netherlands)
- IMIP Andrea Lopes (Brazil)
- Institut Catalá d’Oncologia Badalona (Spain)
- Instituto Brasileiro de Controle do Câncer (Brazil)
- Instituto Câncer do Estado de São Paulo (Brazil)
- Instituto Valenciano de Oncología (Spain)
- Instituto do Câncer e Transplante (Brazil)
- Isala Ziekenhuis (The Netherlands)
- Jewish General Hospital (Canada)
- Juravinski Cancer Centre (Canada)
- Kantonsspital Grabünden (Switzerland)
- Kantonsspital St. Gallen (Switzerland)
- Lagos State University Teaching Hospital (Nigeria)
- Lancashire Teaching Hospitals NHS Foundation Trust (UK)
- Lister Hospital (UK)
- MC Haaglanden (The Netherlands)
- Maasstad Ziekenhuis (The Netherlands)
- Macquarie University Hospital (Australia)
- Mount Vernon Cancer Centre (UK)
- Nederlands Kanker Instituut / Antoni van Leeuwenhoek Ziekenhuis (The Netherlands)
- Noordwest Ziekenhuisgroep (NWZ) Alkmaar (The Netherlands)
- Northern Health (Australia)
- Onkozentrum Zürich (Switzerland)
- Oslo University Hospital (Norway)
- Ottawa Hospital Cancer Centre (Canada)
- Peter MacCallum Cancer Centre (Australia)
- Princess Alexandra Hospital (Australia)
- Princess Margaret Cancer Center (Canada)
- Prostate Cancer Centre (Canada)
- Redland Hospital (Australia)
- Rosebank Oncology (South Africa)
- Royal Brisbane & Women’s Hospital (Australia)
- Servicio de Salud del Principado de Asturias, SESPA (Spain)
- Sheffield Teaching Hospitals NHS Foundation Trust (UK)
- Skåne University Hospital (Sweden)
- Sligo University Hospital (Ireland)
- Sociedade Campineira de Educação e Instrução (SCEI) (Brazil)
- South Tyneside District Hospital (UK)
- St. Vincent’s Hospital Sydney (Australia)
- St. Vincent’s University Hospital (Ireland)
- Steve Biko Academic Hospital (South Africa)
- Stichting Amphia (The Netherlands)
- Stichting Ziekenhuisgroep Twente (ZGT) (The Netherlands)
- Sunderland Royal Hospital (UK)
- Tacchini Hospital (Brazil)
- Tallaght University Hospital (Ireland)
- Ter Gooi Ziekenhuis (The Netherlands)
- The Canberra Hospital (Australia)
- The Christie NHS Foundation Trust (UK)
- The Royal Marsden NHS Foundation Trust (UK)
- The University Of the West Indies – Mona Campus (Jamaica)
- The University of the West Indies – Cave Hill Campus (Barbados)
- Umeå University Hospital (Sweden)
- University Hospital Southampton NHS Foundation Trust (UK)
- University Hospitals of Morecambe Bay NHS Trust (UK)
- University of Ilorin Teaching Hospital (Nigeria)
- University of Maiduguri Teaching Hospital (Nigeria)
- University of Nairobi (Kenya)
- Universitätsspital Basel (Switzerland)
- Universitätsspital Zürich (Switzerland)
- Vall D'Hebron Institut d'Oncologia (VHIO) (Spain)
- Velindre Cancer Centre (UK)
- Westmead Hospital (Australia)
- Örebro University Hospital (Sweden)